Therapeutic Area | MeSH |
---|---|
nervous system diseases | D009422 |
diagnosis | D003933 |
mental disorders | D001523 |
Brand Name | Status | Last Update |
---|---|---|
datscan | New Drug Application | 2024-01-10 |
ioflupane i 123 | ANDA | 2022-12-16 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinsonian disorders | D020734 | — | G20.C | — | — | 1 | 1 | 1 | 3 |
Syndrome | D013577 | — | — | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinson disease | D010300 | EFO_0002508 | G20 | 1 | — | 1 | — | 4 | 6 |
Essential tremor | D020329 | EFO_0003108 | G25.0 | — | — | 1 | — | 1 | 2 |
Tremor | D014202 | — | R25.1 | — | — | 1 | — | 1 | 2 |
Shy-drager syndrome | D012791 | EFO_1001050 | — | — | — | 1 | — | — | 1 |
Multiple system atrophy | D019578 | — | — | — | — | 1 | — | — | 1 |
Atrophy | D001284 | — | — | — | — | 1 | — | — | 1 |
Progressive supranuclear palsy | D013494 | EFO_0002512 | G23.1 | — | — | 1 | — | — | 1 |
Vascular dementia | D015140 | — | F01 | — | — | 1 | — | — | 1 |
Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | 1 | — | — | 1 |
Lewy body disease | D020961 | EFO_0006792 | G31.83 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Movement disorders | D009069 | EFO_0004280 | G25 | — | — | — | — | 1 | 1 |
Wounds and injuries | D014947 | — | T14.8 | — | — | — | — | 1 | 1 |
Traumatic brain injuries | D000070642 | — | S06 | — | — | — | — | 1 | 1 |
Brain injuries | D001930 | — | S06.9 | — | — | — | — | 1 | 1 |
Drug common name | Ioflupane i 123 |
INN | ioflupane (123i) |
Description | Ioflupane I(123) is an azabicycloalkane that is ecgonine methyl ester in which the N-methyl group is replaced by 3-fluoropropyl and the 3beta-hydroxy group is replaced by 4-((123)I)iodophenyl. Used for the imaging of dopamine transporters in the brain of adult patients with potential Parkinsonian Syndromes. It has a role as a radioactive imaging agent and a radiopharmaceutical. It is an azabicycloalkane, an organofluorine compound and a methyl ester. It is functionally related to an ecgonine. |
Classification | Small molecule |
Drug class | iodine-containing contrast media |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | COC(=O)[C@H]1[C@@H](c2ccc([123I])cc2)C[C@@H]2CC[C@H]1N2CCCF |
PDB | — |
CAS-ID | 155798-07-5 |
RxCUI | — |
ChEMBL ID | CHEMBL3989517 |
ChEBI ID | — |
PubChem CID | 3086674 |
DrugBank | DB08824 |
UNII ID | 3MM99T8R5Q (ChemIDplus, GSRS) |